Mesprit first appeared in Pokémon Platinum - Episode 49: Head Honchkrow, where it was shown kidnapped, along with the rest of the Lake Trio, by Team Galactic, but it was later freed by Emile. Mesprit, along with Uxie and Azelf, later assisted Emile against Cyrus. Later, in Episode 56: Emotion VS Logic, Emile and his team caught Mesprit.
- Charm (Episode 56 - Present)
- Future Sight (Episode 56 - Present)
- Lucky Chant (Episode 56 - Present)
- Extrasensory (Episode 56 - Present)
- Mesprit was the only of the Lake Trio not to be caught in a cave lake.
- Mesprit is the first Roaming Legendary encountered in Platinum.